Heartworm infestation is a disease in continuous geographic expansion. New cases are signaled each year in different countries, both in humans and dogs. This is a case report of a 45 kg, 10 year old, male, Argentinian Dog presented to consultation with pyuria and urinary incontinence. All blood and urinary analyses were made, and the results showed at microscopy examination of the blood smear microfilaria without any renal and hepatic functional abnormalities in biochemistry analyses. Urine cytological examinations detected small quantity of hemoglobin with pyuria, cristaluria, bacteriuria and cells from the wall of the bladder and microfilaria. The imagistic and functional kidney status did not show any indices to suspect renal failure. Because of that, we consider that the presence of microfilariuria may be explained only if we take in count the transparietal migration. To the authors knowledge this is the first report in literature in which an ectopic (urinary) presence of microfilaria is seen in the absence of a concomitant renal failure.

This study concerns experimental activities at in fine arts schools involving health and safety risks for artists, teachers and students, especially those carried out in the studios located in educational institutions. The project initially intends to promote quality research on issues concerning health safety and environment sustainable procedures, art materials and products; this includes products use and handling, recycling and waste management in art school studios and laboratories. Latter on, at a second stage, these findings would be made extensive to the art community. There is sufficient empirical evidence that a number of substances, products and materials frequently used in fine arts are either hazardous or suspected to be hazardous and can often cause health problems thus it becomes necessary to implement a health and safety and sustainable procedure to handle them.

Abstract
Introduction: CRM consists of three main parts: Customer, Relationship and Management. Among the three mentioned factors, the “Relationship” process forms the focal sector. According to the hypothesis of this study, “customer’s organizational visiting” has a significant role on their satisfaction.
The objective of this study was to investigate the impact of “customer’s organizational visiting” on Consumer/ Provider Attachment (CPA) in the framework of Customer Relationship Management (CRM) system.
Methods: The study is a survey research that uses correlation method by two researcher made questionnaires that included 46 questions. Experts confirmed the validity and reliability of the questionnaires was calculated by Cronbach\'s alpha. All of telecommunications experts who are using the products were among Population. The sample size was 350 subjects that were randomly selected. Both descriptive and inferential statistics methods have been used to analyze data.
Results and conclusion: The results of the hypothesis testing show that null hypothesis rejected and the alternative-hypothesis accepted. The results show that “customer’s organizational visiting” increases their satisfaction. Regardless of its administrative details “customer’s organizational visiting” can be considered among the most powerful Customer Relationship Management (CRM) tools which tend to Consumer/Provider Attachment (CPA).
Keywords: organizational visiting, Consumer/ Provider Attachment (CPA), CRM.

Background and Objective: We previously showed that the calcium-binding protein S100A4 is overexpressed and related to metastasis in hepatocellular carcinoma (HCC).However, whether S100A4 participates in the regulation of metastasis and its mechanisms in HCC is mostly unknown. Given the associations of S100A4 ,nuclear factor-kB (NF-kB/RelA) and MMP-9 with metastasis in a variety of malignancies, we explored a potential role of S100A4 in HCC metastasis and its mechanism. Methods: 20 patients with HCC invasion (Lymph node metastasis ,micro¬vascular invasion, major portal vein invasion and intrahepatic me¬tastasis) and 20 patients without HCC invasion were included. These tissues were detected for the expression of S100A4, NF-kB/RelA and MMP-9 by immunohistochemistry and quantitative real time polymerase chain reaction (Q-PCR).Correlation between the expressions of S100A4, NF-kB/RelA and MMP-9 with the invasion was analysed. The expressions of S100A4, nuclear factor-kB and MMP-9 was evaluated in HepG2 cell by western blot and immunohistochemistry. HepG2 cells were stably transfected with S100A4-specific small interfering RNA (S100A4 siRNA) to knockdown of S100A4 ,then transiently transfected with S100A4 cDNA to rescure the S100A4 level and evaluated for effects on invasion and expression analysis for molecules involved in invasion.After the HepG2 cells recurred the S100A4 levels, the HepG2 cells was treated with 5 uM PDTC (a selective NF κ B inhibitor) to inhibit the NF-kB activity,or treated with the BB94(a MMPs inhibitor) to inhibit the MMP-9 activity. The expression analysis for molecules involved in invasion was analyzed. Results: A significant increase of S100A4, NF-kB/RelA and MMP-9 expression in HCC tissues with invasion than that of without invasion. A positive correlation was observed between S100A4, NF-kB/RelA,MMP-9 and invasion,respectively. In addition,S100A4 was positively correlated with NF-kB and MMP-9. S100A4 siRNA mediated knockdown of S100A4 in HepG2 cells resulted in significant reduction in the NF-kB activity and MMP-9 expression,and dramatically decreased its invasion. Moreover, the HepG2 cell metastatic potential was rescued by overexpression of S100A4 completely,at the same time, the NF-kB activity and MMP-9 expression was also increased. Pretreatment with PDTC or BB94 was observed to significantly reduce NF-kB activity and MMP-9 expression and dramatically decreased S100A4 -induced invasion. Conclusion: Our findings indicate that S100A4 contributes to HCC metastasis by activation of NF-kB dependant MMP-9 expression,suggesting S100A4 as a novel diagnostic biomarker and therapeutic target in HCC.

Pesticides, heavy metals and detergents are major cause of concern to aquatic environment because of their toxicity and tendency to accumulate in the organism. These concentrations may sometimes reach to the lethal levels causing mortality in fishes which is harmful for humans when consumed by them. Effect of Chlorpyrifos concentration on enzyme activities in the liver of an air berating fish, Channa punctatus (Bloch) exhibited notable alteration. The median lethal concentration (LC50) for Chlorpyrifos pesticide was analyzed statistically by log dose / probit regression line method (APHA, 1971). Acid and Alkaline phosphatase enzymes in liver was estimated quantitatively by Fisk and Subbarow (1925). The selected sub lethal concentration on the experimental protocol were 10 PPM and 20 PPM for exposure of 10, 20 and 30 days respectively Chlorpyrifos pesticides caused significantly (P<C 0. 05) increase in the activity of acid and alkaline phosphates enzymes in the liver of treated fish, Channa punctatus ((Bloch). When compared with the control value. The alternation is acid and alkaline phosphatase enzymes in liver was significantly (P<O. 05) due to pesticide toxic stress.

Genomic repositories increasingly include individual as well as reference sequences, which tries to share near-identical and long identical strings of nucleotides. The sequential processing used by many compression algorithms and the volumes of data involved in compression, mean that these long-range repetitions of sequences are not detected. In this paper authors have shown that a new method of dictionary construction for compression has been very effective in long-range repetition detection making it ideal for compressing very large DNA data sets. The results have shown that improved COMRAD method is able to compress much larger data sets than existing DNA compression algorithms and able to detect repetition over a much longer range than existing general-purpose dictionary-based compression algorithms. Also authors have try to shown experimentally with the help of comparison tables and line graph that the method is effective and many improvements can be made to the general idea to create a very powerful and extendible compression algorithm for compressing and searching in very large data sets.

Concrete is widely used in structural engineering with its high compressive strength, low cost and abundant raw material. But common concrete has some shortcomings, for example, low tensile and flexural strength, poor toughness, high brittleness, and so on that restrict its application. To overcome these deficiencies, additional materials are added to improve the performance of concrete. A Nano admixture is a composite material that has been developed in recent years. It has been successfully used in construction with its excellent flexural tensile strength, permeability and so on. An attempt has been made in this paper to provide the advantages and benefits of using nano admixtures in concrete for a variety of applications. The use of admixtures help in modifying properties of concrete both in plastic and hardened stage and thus results into a more durable concrete. The main purpose of this investigation is to study the effects of nano clay on the compressive, split tensile and flexural strength of concrete. Concrete specimens were casted with and without nano clay and tested after 7 and 28 days water curing. Experimental results show that addition of admixtures improves the performance of concrete.

Ankle joint is one of the most complicated anatomic/functional structures of locomotor aparatus.The upper ankle joint (talocruralis) connects lower end of shin/bone (tibia) and fibula with ankle bone (talus).It represents the connection between lower leg bones and foot bones.The upper and lower ankle joints make functional,anatomic and clinical whole,not only in physiological conditions but in most injuries.Distorsion is the most frequent type of ankle joint injury.It is actually the set of injuries of ligaments,joint capsule and attachement of muscle tendon in the motor power.The foot inversion is the most common injury mechanism,and the foot can be in supination and adduction.There have been 37 examinees obserevd.All of the them have suffered from ankle joint injury,of male and female gender,18-35 years old.The examinees with clinical and radiographic diagnosis of sprained ankle were observed in emergency room and Orthopedic clinic in Podgorica.The results of our study are surch that points the most frequent injuries at workers with distorsion of ankle joint in lateral ligament complex injury,as weel as the sprains of medium level.
The most common ways of being injured in doing different works has been while walking on flat surface.The exception is the injury caused by running in doing work demanding a lot of movements.

Compression of hyperspectral image (HSI) is an important issue in remote sensing applications due to its huge data size. An efficient technique for hyperspectral image compression is proposed based on Discrete Wavelet Transform (DWT) and Tucker Decomposition (TD) with Adaptive Least Squares (ALS) method. This technique exploits both the spatial and spectral information in the images. ALS method is used to compute the TD which is applied on the DWT coefficients of HSI spectral bands. DWT is used to segment the HSIs into various sub-images, while TD is used to conserve the energy of the sub-images. Run length encoding (RLE) performs quantization of the component matrices and encoding of core tensors. The experiments are conducted for HSI of various compressions with HSI compression based on DWT, TD with ALS method and HSI compression methods based on lossless JPEG (JPEG-LS), JPEG2000, SPECK (Set Partitioning Embedded Block), OB (Object Based) - SPECK, and 3D-SPECK and the results of our work are found to be good in terms of compression ratio (CR) and Peak Signal-to-Noise Ratio (PSNR).